The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
Oct. 05, 2012
Applicant:
Cornell University, Ithaca, NY (US);
Inventors:
Hening Lin, Ithaca, NY (US);
Bin He, Ithaca, NY (US);
Assignee:
CORNELL UNIVERSITY, Ithaca, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07C 327/42 (2006.01); A61K 31/16 (2006.01);
U.S. Cl.
CPC ...
C07C 327/42 (2013.01); A61K 31/16 (2013.01);
Abstract
The instant application describes novel compounds that modulate (in particular, inhibit) Sirt, with structures according to Formulas (1) and (2) provided herein. The invention is also directed to pharmaceutical compositions thereof, methods of treatment (i.e., cancer and neurodegenerative disease) by administration of the modulating compounds, assay methods for finding modulators of Sirt, and kits for practicing the assay method.