The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
Jun. 09, 2014
Abbott Cardiovascular Systems Inc., Santa Clara, CA (US);
Deborah Kilpatrick, Los Altos, CA (US);
Syed Faiyaz Ahmed Hossainy, Hayward, CA (US);
Irina Astafieva, Palo Alto, CA (US);
Florian N. Ludwig, Hilversum, NL;
Paul M. Consigny, San Jose, CA (US);
Jeffrey T. Ellis, San Francisco, CA (US);
Florencia Lim, Union City, CA (US);
Abbott Cardiovascular Systems Inc., Santa Clara, CA (US);
Abstract
A method including introducing into a blood stream a delipidated high density lipoprotein (HDL) and a bioactive agent. A composition including a delipidated high density lipoprotein (HDL) and an auxiliary agent in a form suitable for delivery into a blood vessel. A composition including Apo A1 comprising a hydrophobic ligand suitable to interact with cell surface binding sites. A composition including Apo A1 and an agent selected to one of increase the ATP-binding cassette protein 1 (ABCA1) transporter expression in macrophages and protect ABCA1 from thiol-mediated degradation.