The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
Feb. 25, 2011
John D. Lambris, Philadelphia, PA (US);
Fletcher B. Taylor, Pinetops, NC (US);
Florea Lupu, Oklahoma City, OK (US);
Gary Kinasewitz, Edmond, OK (US);
John D. Lambris, Philadelphia, PA (US);
Fletcher B. Taylor, Pinetops, NC (US);
Florea Lupu, Oklahoma City, OK (US);
Gary Kinasewitz, Edmond, OK (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
Methods for the treatment of sepsis with complement inhibitors are disclosed. In particular, C3 inhibitors, such as Compstatin and Compstatin analogs, are administered at various times following the onset of sepsis to alleviate tissue damage and organ failure, which are hallmarks of the second, extravascular stage of sepsis. Combination therapies for comprehensive treatment of sepsis are also disclosed. Pharmaceutical compositions and kits for use in the methods are disclosed as well.