The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2016

Filed:

Nov. 24, 2014
Applicants:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

University of Miami, Miami, FL (US);

Inventors:

Nathanael Gray, Boston, MA (US);

Hwan Geun Choi, Chestnut Hill, MA (US);

Xianming Deng, Brookline, MA (US);

Jianming Zhang, Cambridge, MA (US);

Izidore Lossos, Aventura, FL (US);

Assignees:

Dana-Farber Cancer Institute, Inc., Boston, MA (US);

University of Miami, Miami, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/496 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 239/42 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); C07D 239/42 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to novel compounds which are able to modulate b-raf kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.


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