The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Oct. 19, 2012
Applicants:
Arkray, Inc., Kyoto, JP;
Ultizyme International Ltd., Tokyo, JP;
Inventor:
Koji Sode, Tokyo, JP;
Assignees:
ARKRAY, Inc., Kyoto, JP;
Ultizyme International Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12Q 1/00 (2006.01); C12N 9/02 (2006.01); C12N 9/04 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/006 (2013.01); C12N 9/0004 (2013.01); C12N 9/0006 (2013.01); C12Y 101/05002 (2013.01); C07K 2319/00 (2013.01);
Abstract
A fusion protein of pyrroloquinoline quinone glucose dehydrogenase (PQQGDH) and a cytochrome is disclosed. PQQGDH is, for example, a water-soluble PQQGDH derived from. The cytochrome is, for example, an electron transfer domain of quinohemoprotein ethanol dehydrogenase from. The fusion protein of the present invention shows intramolecular electron transfer from PQQ, a redox center, to the cytochrome, which allow construction of a direct electron transfer-type glucose sensor which requires no electron mediators.