The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Feb. 17, 2010
Applicants:
Jesper Mortensen Haaning, Redwood City, CA (US);
Kim Vilbour Andersen, Broenshoej, DK;
Inventors:
Jesper Mortensen Haaning, Redwood City, CA (US);
Kim Vilbour Andersen, Broenshoej, DK;
Assignee:
BAYER HEALTHCARE LLC, Whippany, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6437 (2013.01); C12Y 304/21021 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to novel polypeptide variants of factor VII (FVII) or factor VIIa (FVIIa) polypeptides, where said variants comprise an amino acid substitution in position 10 and 32 and where said variants further comprise a sugar moiety covalently attached to an introduced in vivo N-glycosylation site located outside of the Gla domain. Such polypeptide variants are useful in therapy, in particular for the treatment of a variety of coagulation-related disorders, such as trauma.