The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Jun. 05, 2008
Applicants:
Ulrich Hersel, Heidelberg, DE;
Harald Rau, Heidelberg, DE;
Dirk Vetter, Heidelberg, DE;
Thomas Wegge, Heidelberg, DE;
Inventors:
Ulrich Hersel, Heidelberg, DE;
Harald Rau, Heidelberg, DE;
Dirk Vetter, Heidelberg, DE;
Thomas Wegge, Heidelberg, DE;
Assignee:
SANOFI-AVENTIS DEUTSCHLAND GMBH, Deutschland, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/575 (2006.01); A61K 47/48 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/57563 (2013.01); A61K 47/4823 (2013.01); A61K 47/48215 (2013.01); A61K 47/48238 (2013.01); A61K 47/48284 (2013.01); A61K 47/48338 (2013.01); A61K 38/00 (2013.01);
Abstract
Long-acting polymer exendin-4 or exendin agonist derivatives of the formula Pol-L-E are provided wherein Pol is a polymer, L is a releasing linker undergoing slow autohydrolysis and E is an exendin or exendin agonist. These exendin or exendin agonists are slowly released from Pol-L upon administration to a living organism. The derivatives are useful e.g. for the treatment of diabetes mellitus.