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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9353162 B1

PDFFull Text
Date of Patent:
May. 31, 2016

Filed:

Dec. 17, 2012

Disease-associated proteins

Applicant:

Novartis Ag, Basel, CH;

Inventors:

Thirry Léveillard, Maisons-Alfort, FR;

Jose Alain Sahel, Paris, FR;

Saddek Mohand-Said, Paris, FR;

Olivier Poch, Strasbourg, FR;

David Hicks, Strasbourg, FR;

Carlos Alvarez, Riehen, CH;

Assignees:

NOVARTIS AG, Basel, CH;

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Paris, FR;

Attorney:

Andrew Holmes, Esq.

Primary Examiner:

Chang-Yu Wang

Int. Cl.
CPC ...
C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); A61K 38/18 (2006.01); C07K 14/475 (2006.01); C07K 14/48 (2006.01); A61K 38/00 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/435 (2013.01); C07K 14/47 (2013.01); Y10T 436/143333 (2015.01);
Abstract

Disclosed are methods and compositions for early diagnosis, monitoring and treatment of an ocular disorder. In particular, the invention relates to a novel protein, that is differentially transcribed and expressed in subjects suffering from retinal dystrophies and the like, such as retinal dystrophy and age-related macular degeneration compared with healthy subjects, antibodies which recognize this protein, and methods for diagnosing such conditions.

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