The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Oct. 25, 2013
Applicant:
Newsouth Innovations Pty Limited, UNSW Sydney, AU;
Inventor:
Philip John Hogg, Randwick, AU;
Assignee:
NewSouth Innovations Pty Limited, Sydney, AU;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/555 (2006.01); C07K 7/06 (2006.01); A61K 31/285 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); C07F 9/78 (2006.01); C07F 9/80 (2006.01); C07F 9/82 (2006.01); C07F 5/06 (2006.01); C07K 5/08 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 31/285 (2013.01); C07F 5/06 (2013.01); C07F 9/78 (2013.01); C07F 9/803 (2013.01); C07F 9/82 (2013.01); C07K 5/08 (2013.01); G01N 33/5011 (2013.01); G01N 33/5079 (2013.01); G01N 33/574 (2013.01); G01N 33/6872 (2013.01); G01N 2333/515 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present invention relates to process for identifying a compound which induces the mitochondrial permeability transition (MPT) in proliferating cells, wherein said process comprises contacting a cell or cell extract with a compound, determining whether the compound binds to adenine nucleotide translocator (ANT), and determining whether the compound selectively induces the MPT in proliferating cells.