The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Dec. 02, 2013
Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
Applicant:
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Inventors:
Dane Goff, Redwood City, CA (US);
Jing Zhang, Foster City, CA (US);
Rajinder Singh, Belmont, CA (US);
Sacha Holland, San Francisco, CA (US);
Jiaxin Yu, San Carlos, CA (US);
Pingyu Ding, Foster City, CA (US);
Joane Litvak, Oakland, CA (US);
Assignee:
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/14 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 453/06 (2006.01); C07D 409/14 (2006.01); C07D 471/18 (2006.01); C07D 495/04 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); C07D 249/14 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 409/14 (2013.01); C07D 453/06 (2013.01); C07D 471/18 (2013.01);
Abstract
Bridged bicyclic aryl or heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.