The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Aug. 06, 2013
Sunil Kumar Singh, Hyderabad, IN;
Sachin Srivastava, N. Mumbai, IN;
Shekhar Bhaskar Bhirud, Mumbai, IN;
Sunil Kumar Singh, Hyderabad, IN;
Sachin Srivastava, N. Mumbai, IN;
Shekhar Bhaskar Bhirud, Mumbai, IN;
Glenmark Pharmaceuticals Limited, Mombai, IN;
Abstract
Provided is a process for the preparation of linagliptin of Formula I, comprising deprotecting a compound of Formula II wherein Rand Rtogether with the nitrogen to which they are attached form a phthalimido group, wherein the aromatic ring of the phthalimido group is substituted with one or more Rsubstituents selected from the group consisting of halogen, alkyi, nitro and amino; or Ris H and Ris selected from the group consisting of trialkylsilyl, 2-trialkylsilylethoxycarbamates, acetyl, trihaloacetyl, 9-fluorenylmethoxycarbonyl, trityl, alkylsulfonyl, arylsulfonyl, diphenylphosphine and sulfonylethoxycarbonyl.