The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2016

Filed:

Apr. 26, 2013
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

John J. Acton, III, Cranford, NJ (US);

Feng Ye, Scotch Plains, NJ (US);

Petr Vachal, Summit, NJ (US);

Deyou Sha, Yardley, PA (US);

James F. Dropinski, Colts Neck, NJ (US);

Lin Chu, Scotch Plains, NJ (US);

Debra Ondeyka, Fanwood, NJ (US);

Alexander J. Kim, Morganville, NJ (US);

Vincent J. Colandrea, North Brunswick, NJ (US);

Yi Zang, Princeton Junction, NJ (US);

Fengqi Zhang, Edison, NJ (US);

Guizhen Dong, Cranford, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C07D 413/14 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/444 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/444 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 413/14 (2013.01);
Abstract

Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and may be useful for raising HDL-cholesterol and reducing LDL-cholesterol in human patients and for treating or preventing atherosclerosis.


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