The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Mar. 26, 2014
Applicants:
Saint Louis University, St. Louis, MO (US);
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, CN;
Inventors:
Xiaoping Chen, Guangzhou, CN;
Ke Ding, Guangzhou, CN;
Marvin J. Meyers, Wentzville, MO (US);
Micky D. Tortorella, Guangzhou, CN;
Jing Xu, Guangzhou, CN;
Assignees:
Saint Louis University, St. Louis, MO (US);
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); C07D 233/02 (2006.01); C07D 401/10 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); C07D 233/02 (2013.01); C07D 401/10 (2013.01); C07D 403/04 (2013.01);
Abstract
The present invention provides aminohydantoin anti-malarial agents. In some embodiments, these agents have the property of functions of targeting malarial aspartic proteases while at the same time having low activity against human BACE. Methods of employing such agents are also provided.