The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Nov. 21, 2012
The Regents of the University of California, Oakland, CA (US);
Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;
Universita Degli Studi Di Parma, Parma, IT;
Universita Degli Studi Di Urbino “carlo Bo”, Urbino, IT;
Daniele Piomelli, Irvine, CA (US);
Tiziano Bandiera, Gambolo, IT;
Marco Mor, Ghedi, IT;
Giorgio Tarzia, Petriano, IT;
Fabio Bertozzi, Genoa, IT;
Stefano Ponzano, Florence, IT;
The Regents of the University of California, Oakland, CA (US);
Fondazione Istituto Italiano Di Technologia, Genoa, IT;
Universita Degli Studi Di Parma, Parma, IT;
Universita Degli Studi Di Urbino “Carlo Bo”, Urbino, IT;
Abstract
The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.