The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2016
Filed:
Oct. 23, 2012
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Fajun Nan, Shanghai, CN;
Min Li, Shanghai, CN;
Zhaobing Gao, Shanghai, CN;
Fei Chen, Shanghai, CN;
Yangming Zhang, Shanghai, CN;
Pingzheng Zhou, Shanghai, CN;
Haining Hu, Shanghai, CN;
Haiyan Xu, Shanghai, CN;
Sheng Liu, Shanghai, CN;
Abstract
The present invention provides compounds having the structure represented by general formula I, pharmaceutically acceptable salts thereofagonist, preparation methods therefor and a use thereof in the preparation of a medicine for the treatment of nervous system diseases. The compounds or pharmaceutical compositions thereof can be used as the KCNQ potassium channel agonist for treating nervous system diseases. Compared to retigabine, a compound in the prior art, the compound of the present invention have the same or better therapeutic effect, are easier for synthesis and storage, and less prone to oxidate deterioration.