The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9352052 B1

PDF
Full Text
Expired
Date of Patent:
May. 31, 2016

Filed:

Nov. 11, 2010
Applicant:

Kazuto Kobayashi, Fukushima, JP;

Inventor:

Kazuto Kobayashi, Fukushima, JP;

Assignee:

JAPAN SCIENCE AND TECHNOLOGY AGENCY, Kawaguchi-Shi, Saitama, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A01N 63/00 (2006.01); A61K 48/00 (2006.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0075 (2013.01); C07K 14/005 (2013.01); C12N 15/86 (2013.01); C12N 2740/16045 (2013.01); C12N 2740/16052 (2013.01); C12N 2760/20122 (2013.01); C12N 2760/20222 (2013.01); C12N 2810/6081 (2013.01);
Abstract

Provided is a lentiviral vector system which sustains a high-frequency retrograde transportation ability in animal brain and has a higher titer. A kit for preparing a retrograde transport viral vector, which comprises: (1) a packaging plasmid containing the gag gene and pol gene of HIV-1; (2) a packaging plasmid containing an accessory gene of HIV-1; (3) a transfer plasmid containing a target gene; and (4) an envelope plasmid containing, as an envelope gene, a gene encoding a fused polypeptide comprising the extracellular domain of rabies virus glycoprotein (RV-G), the transmembrane domain of rabies virus glycoprotein (RV-G) or vesicular stomatitis virus glycoprotein (VSV-G) and the intracellular domain of vesicular stomatitis virus glycoprotein (VSV-G).


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Kobayashi, Kazuto. (2016). Retrograde transport viral vector system having envelope comprising fused glycoprotein (U.S. Patent No. 9352052). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9352052

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