The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Dec. 06, 2010
Filippo Bastia, Sozzigalli di Soliera, IT;
Donato Altomare, Giovinazzo, IT;
Alfredo Di Leo, Monopoli, IT;
Maria Teresa Rotelli, Noicattaro, IT;
Michele Barone, Bari, IT;
Filippo Bastia, Sozzigalli di Soliera, IT;
Donato Altomare, Giovinazzo, IT;
Alfredo Di Leo, Monopoli, IT;
Maria Teresa Rotelli, Noicattaro, IT;
Michele Barone, Bari, IT;
THD S.p.A., Correggio, IT;
Abstract
The present invention relates to a method for diagnosing a carcinoma or a residual disease associated thereto, or for the prognosis of a carcinoma, or for monitoring the effectiveness of an anti-tumour therapy directed against a carcinoma, or for monitoring the follow-up of an individual affected by a carcinoma, in particular colorectal carcinoma, carcinoma of the stomach, mammary carcinoma, pulmonary carcinoma or carcinoma of the prostate, carcinoma of the liver, carcinoma of the ovary, carcinoma of the kidney, carcinoma of the thyroid, carcinoma of the bladder or carcinoma of the pancreas. The method of the invention consists in placing adult stem cells in contact with a sample of a haemo-derivative of the individual to be analyzed and in verifying the expression of at least an epithelial marker in the stem cells by means of immunofluorescence, immunohistochemistry, ELISA or RT-PCR.