The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Feb. 24, 2014
Applicants:
King's College London, London, GB;
Guy's & St. Thomas' Nhs Foundation Trust, London, GB;
Inventors:
Assignees:
King's College London, London, GB;
Guy's St. Thomas' NHS Foundation Trust, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01); G01N 33/68 (2006.01); G01N 33/72 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/37 (2013.01); G01N 33/6848 (2013.01); G01N 33/721 (2013.01); G01N 2333/976 (2013.01); G01N 2560/00 (2013.01);
Abstract
A method for screening for variant peptides uses mass spectrometry (MS). A system and a kit may be used for performing the method. Proteins in a sample are digested to form a defined series of peptides. The defined series of peptides are ionized. The ionized species are subjected to collision induced dissociation. Species of known mass/charge ratio are detected to confirm the presence of the protein variant in the original sample.