The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2016

Filed:

Jun. 13, 2013
Applicant:

E I Du Pont DE Nemours and Company, Wilmington, DE (US);

Inventors:

Michael W Bostick, Wilmington, DE (US);

Narendra S Yadav, Wilmington, DE (US);

Hongxiang Zhang, Chadds Ford, PA (US);

Quinn Qun Zhu, West Chester, PA (US);

Assignee:

E I DU PONT DE NEMOURS AND COMPANY, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C12N 15/81 (2006.01); C12P 7/64 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12P 7/6427 (2013.01); C12N 9/1029 (2013.01); C12N 15/815 (2013.01); Y02P 20/52 (2015.11);
Abstract

Mutant acyl-CoA:lysophosphatidylcholine acyltransferases ['LPCATs'] having the ability to convert acyl-CoA+1-acyl-sn-glycero-3-phosphocholine to CoA+1,2-diacyl-sn-glycero-3-phosphocholine (EC 2.3.1.23) are disclosed herein. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding mutant LPCATs, along with a method of making long chain polyunsaturated fatty acids ['PUFAs'] using these mutant LPCATs in oleaginous yeast, are also disclosed.


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