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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9347050 B1

PDFFull Text
Date of Patent:
May. 24, 2016

Filed:

Sep. 29, 2011

Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated n-glycans and methods of facilitating mammalian cellular uptake of glycoproteins

Applicants:

Kathleen Camilla Telesphore Alida Maria Piens, Gent, BE;

Wouter Vervecken, Landskouter, BE;

Albena Vergilieva Valevska, Astene, BE;

Gwenda Noëlla Pynaert, Aalter, BE;

Inventors:

Kathleen Camilla Telesphore Alida Maria Piens, Gent, BE;

Wouter Vervecken, Landskouter, BE;

Albena Vergilieva Valevska, Astene, BE;

Gwenda Noëlla Pynaert, Aalter, BE;

Assignee:

Oxyrane UK Limited, Manchester, GB;

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Julie Ha

Assistant Examiner:

Kristina M Hellman

Int. Cl.
CPC ...
C12P 19/26 (2006.01); C12P 21/00 (2006.01); A61K 38/43 (2006.01); C12N 15/81 (2006.01); C12N 9/10 (2006.01); C12N 9/24 (2006.01); A61K 38/17 (2006.01); A61K 38/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2488 (2013.01); A61K 38/16 (2013.01); A61K 38/1709 (2013.01); C12N 9/2402 (2013.01); C12P 21/005 (2013.01); C12Y 302/01024 (2013.01); A61K 38/00 (2013.01); Y02P 20/52 (2015.11);
Abstract

The invention provides mannosidases capable of uncapping mannose-1-phospho-6-mannose moieties and demannosylating phosphorylated N-glycans, methods of using such mannosidases, glycoproteins produced using the methods, as well as methods of facilitating mammalian cellular uptake of glycoproteins.

Find Patent Forward Citations

Piens, Kathleen Camilla Telesphore Alida Maria. (2016). Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated n-glycans and methods of facilitating mammalian cellular uptake of glycoproteins (U.S. Patent No. 9347050). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9347050

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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