The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2016

Filed:

Apr. 11, 2012
Applicants:

Pierre Mourier, Paris, FR;

Christian Viskov, Paris, FR;

Inventors:

Pierre Mourier, Paris, FR;

Christian Viskov, Paris, FR;

Assignee:

SANOFI, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/00 (2006.01); A61K 31/727 (2006.01); G01N 30/86 (2006.01); B01D 15/34 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01); A61K 45/06 (2006.01); B01D 15/18 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0075 (2013.01); A61K 31/727 (2013.01); A61K 45/06 (2013.01); B01D 15/34 (2013.01); B01D 15/363 (2013.01); B01D 15/3823 (2013.01); B01D 15/1878 (2013.01); Y10T 436/143333 (2015.01);
Abstract

The invention relates to sulphated polysaccharides which have the general structure of the constituent polysaccharides of heparin and which have a molecular weight of less than 8000 Daltons, comprising two antithrombin III-binding hexasaccharide sequences corresponding to formula (I) in which: R1 represents an OH group when the hexasaccharide of formula (I) is located at the reducing end of the polysaccharide, or else R1 represents a bond with another saccharide unit of said polysaccharide; R2 represents a hydrogen atom when the hexasaccharide of formula (I) is located at the non-reducing end of the polysaccharide, in which case the bond between carbon atoms 4 and 5 of the first saccharide unit of said hexasaccharide is a double bond, or else R2 represents a bond with another saccharide unit of said polysaccharide, in which case the bond between carbon atoms 4 and 5 of the first saccharide unit is a single bond. Preparation thereof, use thereof as antithrombotic medicaments, and also use thereof in a method for analyzing a sample of a heparin derivative.


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