The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Sep. 19, 2013
Applicant:
Medarex, L.l.c., Princeton, NJ (US);
Inventors:
Jennifer Marie Mataraza, Cambridge, MA (US);
Andrea Van Elsas, Oss, NL;
Alan J. Korman, Piedmont, CA (US);
Edward L. Halk, Sunnyvale, CA (US);
Kent B. Thudium, Oakland, CA (US);
Mark J. Selby, San Francisco, CA (US);
Timothy W. Sproul, Livermore, CA (US);
Heidi N. Leblanc, Mountain View, CA (US);
Assignee:
E. R. SQUIBB & SONS, L.L.C., Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 15/11 (2006.01); C12N 15/79 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); C07K 16/2818 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/77 (2013.01);
Abstract
The present invention relates to binding compounds specific for BTLA and uses thereof. More specifically, the invention relates to fully human antibodies that recognize human BTLA and modulate its activity in cancer, inflammatory, and autoimmune disorders.