The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Apr. 15, 2011
Shin-ichiro Nishimura, Sapporo, JP;
Takahiko Matsushita, Sapporo, JP;
Yoshiaki Miura, Glen Rock, NJ (US);
Shin-Ichiro Nishimura, Sapporo, JP;
Takahiko Matsushita, Sapporo, JP;
Yoshiaki Miura, Glen Rock, NJ (US);
Sumitomo Bakelite Co., Ltd., Tokyo, JP;
Abstract
Cancer-associated O-glycopeptide combination epitopes derived from the VNTR of MUC1 are disclosed. Autoantibodies present in human sera target the combination epitopes and are reduced or absent in cancer patients. The epitopes are useful as therapeutic and immunoprophylactic cancer vaccines. Monoclonal antibodies directed against the epitopes are also useful as immunotherapeutics for treatment and prevention of cancer. Diagnostic methods using the epitopes and antibodies are also disclosed.