The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Jun. 19, 2013
Applicant:
Sandoz Ag, Basel, CH;
Inventors:
Kathrin Hoeferl-Prantz, Kundl, AT;
Wolfgang Felzmann, Kundl, AT;
Thorsten Wilhelm, Kundl, AT;
David Benito-Garagorri, Kundl, AT;
Assignee:
Sandoz AG, Basel, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/04 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 5/107 (2006.01); C07D 403/12 (2006.01); C07K 5/087 (2006.01); C07K 5/083 (2006.01); C07K 5/062 (2006.01); C07C 227/02 (2006.01); C07C 231/02 (2006.01); C07C 231/12 (2006.01); C07C 237/06 (2006.01); C07F 7/18 (2006.01); C07K 1/10 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1016 (2013.01); C07C 227/02 (2013.01); C07C 231/02 (2013.01); C07C 231/12 (2013.01); C07C 237/06 (2013.01); C07D 403/12 (2013.01); C07F 7/1872 (2013.01); C07K 1/10 (2013.01); C07K 5/06034 (2013.01); C07K 5/0808 (2013.01); C07K 5/0812 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention relates to synthetic routes for preparing telaprevir and boceprevir, and its intermediates as well as peptides other than telaprevir. The synthetic routes are based on a Mukaiyama aldol addition reaction of a silyl enol ether or an enolate with an imine. The invention also refers to novel intermediates for preparing telaprevir/boceprevir or other peptides.