The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Mar. 13, 2012
Chongqing Sun, East Windsor, NJ (US);
William R. Ewing, Yardley, PA (US);
Scott A. Bolton, Newtown, PA (US);
Zhengxiang Gu, Princeton, NJ (US);
Yanting Huang, Pennington, NJ (US);
Natesan Murugesan, Princeton Junction, NJ (US);
Yeheng Zhu, Stockton, NJ (US);
Chongqing Sun, East Windsor, NJ (US);
William R. Ewing, Yardley, PA (US);
Scott A. Bolton, Newtown, PA (US);
Zhengxiang Gu, Princeton, NJ (US);
Yanting Huang, Pennington, NJ (US);
Natesan Murugesan, Princeton Junction, NJ (US);
Yeheng Zhu, Stockton, NJ (US);
Bristol-Myers Scuibb Company, Princeton, NJ (US);
Abstract
The present invention provides compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein A is a five to eight membered monocyclic or a nine to twelve membered bicyclic heterocyclic ring, as further defined herein; Y is S, CH, or CH; Z is CH or N; Rand Rare hydrogen or (C-C)alkyl; Ris (C-C)alkoxy, OH, CN, (C-C)alkyl, halogen, or CF; r and s are 0, 1, or 2; and Rand Rare as further defined herein. These compounds are agonists, partial agonists and/or modulators of the NPY4 receptor and may be used for the treatment and prophylaxis of obesity, food intake, and other diseases and conditions modulated by the NPY4 receptor.