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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9346840 B1

PDFFull Text
Date of Patent:
May. 24, 2016

Filed:

Sep. 03, 2014

Cyclopropylamines as lsd1 inhibitors

Applicant:

Glaxosmithkline Intellectual Property (No. 2) Limited, Brentford, GB;

Inventors:

Neil W. Johnson, Collegeville, PA (US);

Jiri Kasparec, Collegeville, PA (US);

Meagan B. Rouse, Collegeville, PA (US);

Xinrong Tian, Collegeville, PA (US);

William Henry Miller, Collegeville, PA (US);

Dominic Suarez, Collegeville, PA (US);

Assignee:

GlaxoSmithKline Intellectual Property (No. 2) Limited, Brentford, Middlesex, GB;

Attorneys:

Duke M. Fitch

Kathryn A. Lutomski

Edward R. Gimmi

Primary Examiner:

Sreeni Padmanabhan

Assistant Examiner:

Sahar Javanmard

Int. Cl.
CPC ...
C07C 211/35 (2006.01); C07D 211/62 (2006.01); C07D 211/26 (2006.01); C07F 9/59 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 413/06 (2006.01); C07D 265/30 (2006.01); C07D 207/09 (2006.01); C07D 211/96 (2006.01); C07D 223/04 (2006.01); C07C 271/24 (2006.01); C07C 211/36 (2006.01); C07F 5/02 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07F 9/591 (2013.01); C07C 211/35 (2013.01); C07C 211/36 (2013.01); C07C 271/24 (2013.01); C07D 207/09 (2013.01); C07D 211/26 (2013.01); C07D 211/62 (2013.01); C07D 211/96 (2013.01); C07D 223/04 (2013.01); C07D 265/30 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 413/06 (2013.01); C07F 5/02 (2013.01); C07F 5/025 (2013.01); C07C 2101/02 (2013.01); C07C 2101/14 (2013.01);
Abstract

This invention relates to the use of cyclopropylamine derivatives for the modulation, notably the inhibition of the activity of Lysine-specific demethylase 1 (LSD1). Suitably, the present invention relates to the use of cyclopropylamines in the treatment of cancer.

Find Patent Forward Citations

Johnson, Neil. (2016). Cyclopropylamines as lsd1 inhibitors (U.S. Patent No. 9346840). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9346840

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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