The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2016

Filed:

Oct. 16, 2013
Applicant:

Board of Supervisors of Louisiana State University and Agricultural, Baton Rouge, LA (US);

Inventors:

Nikhil V. Dhurandhar, Baton Rouge, LA (US);

Bhaskar C. Das, West Nyack, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); C07F 5/04 (2006.01);
U.S. Cl.
CPC ...
C07F 5/04 (2013.01); C07F 5/02 (2013.01); C07F 5/025 (2013.01);
Abstract

A compound includes the structure of general Formula (II), pharmaceutically acceptable salts thereof, and/or solvates thereof: wherein R, R, R, are independently selected from the group consisting of null, hydroxy, alkoxy, and halo, or Rand Rtaken together form a cyclic boronate ester and Ris null; wherein when four bonds to boron are present, boron bears a formal negative charge and the structure further comprises a countercation that is potassium or sodium, X, X, X, and Xare independently selected from the group consisting of O, CH, and N, with the proviso that no more than two of combined O and N are selected, and Z is selected from the group consisting of hydrogen, alkyl, aryl, heteroaryl, and halogen, any of which may be optionally substituted. Such compounds can increase glucose uptake by cells and preferably do not substantially increase adipogenesis.


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