The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Apr. 05, 2012
Weilin Sun, New York, NY (US);
Tony Taldone, New York, NY (US);
Pallav Patel, Philadelphia, PA (US);
Gabriela Chiosis, New York, NY (US);
Weilin Sun, New York, NY (US);
Tony Taldone, New York, NY (US);
Pallav Patel, Philadelphia, PA (US);
Gabriela Chiosis, New York, NY (US);
Sloan-Kettering Institute for Cancer Research, New York, NY (US);
Abstract
The disclosure relates to Compounds of Formulae (IA) and (IB): and pharmaceutically acceptable salts thereof wherein Z, Z, Z, Xa, Xb, Xc, Xd, Y, X, and Xare as defined herein, compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB), and methods to treat or prevent a condition, such cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and IB) in which Xis a leaving for introducing a radiolabeled atom, such asI orI and to methods of using such compounds in the preparation of radiolabeled compounds, particularly for use in imaging.