The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2016

Filed:

Nov. 14, 2012
Applicant:

Array Biopharma Inc., Boulder, CO (US);

Inventors:

Anna Banka, Boulder, CO (US);

Josef R. Bencsik, Boulder, CO (US);

James F. Blake, Boulder, CO (US);

Kin Chiu Fong, Boulder, CO (US);

Martin F. Hentemann, Boulder, CO (US);

Ian S. Mitchell, Boulder, CO (US);

Douglas McCord Sammond, Boulder, CO (US);

Tony P. Tang, Boulder, CO (US);

Eli M. Wallace, Boulder, CO (US);

Rui Xu, Boulder, CO (US);

James Graham, Boulder, CO (US);

Assignee:

ARRAY BIOPHARMA INC., Boulder, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/10 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
C07D 471/10 (2013.01); C07D 487/10 (2013.01);
Abstract

The present invention provides compounds of Formula I including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer.


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