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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9346799 B1

PDFFull Text
Expired
Date of Patent:
May. 24, 2016

Filed:

Oct. 13, 2014

Useful combinations of monobactam antibiotics with beta-lactamase inhibitors

Applicant:

Basilea Pharmaceutica Ag, Basel, CH;

Inventors:

Eric Desarbre, Mulhouse, FR;

Bérangère Gaucher, Mulhouse, FR;

Malcom G. P. Page, Basel, CH;

Patrick Roussel, Mulhouse, FR;

Assignee:

Basilea Pharmaceuticals AG, Basel, CH;

Attorney:
Primary Examiner:

Shirley V Gembeh

Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 417/12 (2006.01); A61K 31/427 (2006.01); C07D 417/04 (2006.01); A61K 31/407 (2006.01); A61K 31/43 (2006.01); A61K 31/4436 (2006.01); A61K 31/545 (2006.01); A61K 31/662 (2006.01); A61K 31/69 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); A61K 31/41 (2006.01); A61K 31/433 (2006.01); A61K 31/4375 (2006.01); A61K 31/444 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/407 (2013.01); A61K 31/41 (2013.01); A61K 31/427 (2013.01); A61K 31/43 (2013.01); A61K 31/433 (2013.01); A61K 31/4375 (2013.01); A61K 31/444 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/545 (2013.01); A61K 31/662 (2013.01); A61K 31/69 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

A pharmaceutical composition, comprising a combination of an antibiotically active compound of the formula (I): with a β-lactamase inhibitor of one of the formulae (II) to (XIII) are active against Gram-negative bacteria, in particular such bacteria which have become resistant against antibiotics such as aztreonam, carumonam and tigemonam. Optionally the compositions may comprise another β-lactamase inhibitor of one of the formulae (II) to (XIII), particularly of formula (V) or formula (VI).

Find Patent Forward Citations

Quick Actions:

Desarbre, Eric. (2016). Useful combinations of monobactam antibiotics with beta-lactamase inhibitors (U.S. Patent No. 9346799). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9346799

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