The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Oct. 01, 2013
Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
Applicant:
Tekmira Pharmaceuticals Corporation, Burnaby, CA;
Inventors:
Muthiah Manoharan, Cambridge, MA (US);
Kallanthottathil G. Rajeev, Cambridge, MA (US);
David Butler, Cambridge, MA (US);
Muthusamy Jayaraman, Cambridge, MA (US);
Assignee:
Tekmira Pharmaceuticals Corporation, Burnaby, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 48/00 (2006.01); C12N 15/11 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48092 (2013.01); A61K 47/48061 (2013.01); A61K 47/48107 (2013.01); A61K 47/48123 (2013.01); A61K 48/0008 (2013.01); C12N 15/111 (2013.01); C12N 15/87 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/322 (2013.01); C12N 2310/346 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01);
Abstract
The invention relates to compositions and methods for site-specific delivery of nucleic acids by combining them with targeting ligands and endosomolytic components.