The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2016

Filed:

Nov. 15, 2012
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Walter J. Storkus, Pittsburgh, PA (US);

Anamika Bose, Kolkata, IN;

Jennifer Lynn Taylor, McDonald, PA (US);

Xi Zhao, Pittsburgh, PA (US);

Devin B. Lowe, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 38/08 (2006.01); A61K 38/17 (2006.01); G01N 33/574 (2006.01); A61K 39/00 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/506 (2013.01); A61K 38/08 (2013.01); A61K 38/1709 (2013.01); A61K 39/0011 (2013.01); G01N 33/574 (2013.01); G01N 33/5743 (2013.01); G01N 33/57438 (2013.01); G01N 33/57446 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55538 (2013.01);
Abstract

Immunogenic peptides from tumor associated stromal cell antigens, including combinations of such peptides, are disclosed herein. In some examples the peptides are useful for methods of eliciting an immune response. In additional examples the peptides are useful for methods of treating cancer. Methods for decreasing vascularization of a tumor using a Protein Delta Homolog 1 (DLK1) protein or a nucleic acid encoding the protein are also disclosed.


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