The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Apr. 25, 2013
Applicants:
Musc Foundation for Research Development, Charleston, SC (US);
University of South Carolina, Columbia, SC (US);
Inventors:
Robert G. Gourdie, Roanoke, VA (US);
Edie C. Goldsmith, Columbia, SC (US);
L. Jane Jourdan, Roanoke, VA (US);
Joshua Matthew Rhett, Charleston, SC (US);
Michael J. Yost, Charleston, SC (US);
Assignees:
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT, Charleston, SC (US);
UNIVERSITY OF SOUTH CAROLINA, Columbia, SC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61L 27/22 (2006.01); A61L 27/54 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61L 27/34 (2006.01); A61L 31/04 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01); A61L 15/32 (2006.01); A61L 15/44 (2006.01); A61L 17/00 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2006.01); C07K 14/47 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); A61K 9/0048 (2013.01); A61K 38/08 (2013.01); A61K 45/06 (2013.01); A61K 47/10 (2013.01); A61L 15/32 (2013.01); A61L 15/44 (2013.01); A61L 17/005 (2013.01); A61L 27/22 (2013.01); A61L 27/34 (2013.01); A61L 27/54 (2013.01); A61L 31/047 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/47 (2013.01); C07K 14/4703 (2013.01); A61K 38/00 (2013.01); A61L 2300/25 (2013.01); A61L 2300/252 (2013.01); A61L 2300/412 (2013.01); A61L 2430/16 (2013.01); C07K 2319/035 (2013.01);
Abstract
Provided are peptides that can inhibit collagen synthesis, processing and/or secretion from scar forming cells or fibroblasts. Also provided are methods for using the peptides to produce an anti-fibrotic, anti-scarring, anti-inflammatory, and/or pro-regenerative effect, e.g., on an injured or diseased tissue.