The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Sep. 11, 2012
Stuart Denham Shumway, Franklin, MA (US);
Carlo Toniatti, Houston, TX (US);
Brian Scott Roberts, Huntsville, AL (US);
Melissa M. Martin, Thousand Oaks, CA (US);
Stuart Denham Shumway, Franklin, MA (US);
Carlo Toniatti, Houston, TX (US);
Brian Scott Roberts, Huntsville, AL (US);
Melissa M. Martin, Thousand Oaks, CA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell lung cancer and ovarian cancer, by administering a combination of a WEE1 inhibitor and a CHK1 inhibitor, wherein the WEE1 inhibitor is MK-1775 or a pharmaceutically acceptable salt thereof, or MK-3652 or a pharmaceutically acceptable salt thereof, and the CHK1 inhibitor is MK-8776 or a pharmaceutically acceptable salt thereof, or SCH900444 or a pharmaceutically acceptable salt thereof.