The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2016
Filed:
Jun. 09, 2010
Applicants:
Chunlin Tao, Los Angeles, CA (US);
Xiaowen Sun, Shanghai, CN;
Hongna Han, Irvine, CA (US);
Lukasz Koroniak, Poznan, PL;
Neil Desai, Los Angeles, CA (US);
Inventors:
Chunlin Tao, Los Angeles, CA (US);
Xiaowen Sun, Shanghai, CN;
Hongna Han, Irvine, CA (US);
Lukasz Koroniak, Poznan, PL;
Neil Desai, Los Angeles, CA (US);
Assignee:
NantBioScience, Inc., Culver City, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 217/16 (2006.01); A61K 31/472 (2006.01); A61K 31/47 (2006.01); A61K 31/517 (2006.01); C07D 239/74 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 31/517 (2013.01); C07D 217/16 (2013.01); C07D 239/74 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 407/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract
The invention provides isoquinoline, quinoline, and quinazoline derivatives to treat a variety of disorders, diseases and pathologic conditions, and more specifically to the use of isoquinoline, quinoline, and quinazoline derivatives to inhibit the hedgehog signaling pathway and to the use of those compounds to the treatment of hyperproliferative diseases and pathologic angiogenesis.