The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2016
Filed:
Jun. 17, 2015
Dh Technologies Development Pte. Ltd., Singapore, SG;
Eth Zürich, Zürich, CH;
Ronald F. Bonner, Newmarket, CA;
Stephen A. Tate, Barrie, CA;
Rudolf Aebersold, Zurich, CH;
Pedro Jose Navarro Alvarez, Zurich, CH;
Oliver Rinner, Zurich, CH;
Lukas Reiter, Wil, CH;
Ludovic Gillet, Zurich, CH;
DH Technologies Development Pte. Ltd., Singapore, SG;
ETH Zürich, , CH;
Abstract
Systems and methods are disclosed for quantitating detectable compounds of a sample. Sample product ion spectra are received for each mass selection window for each time step. The received sample product ion spectra are searched for the presence of known compounds of interest with known product ion spectra by retrieving the known product ion spectra from a library, retrieving the sample product ion spectra corresponding to the precursor mass selection window expected to contain a precursor ion corresponding to the known product ion spectra, generating product ion traces in time for the sample product ion spectra for the known product ion spectra, calculating a score for the product ion traces and product ion spectra that represents how well known product ions and sample product ions match, and calculating a quantitative value for the known compound from the product ion traces when the score exceeds a threshold value.