The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2016

Filed:

May. 29, 2008
Applicants:

Cagri Savran, West Lafayette, IN (US);

Philip Low, West Lafayette, IN (US);

David Thompson, West Lafayette, IN (US);

Walter Henne, West Lafayette, IN (US);

Derek Doorneweerd, West Lafayette, IN (US);

Chun-li Chang, West Lafayette, IN (US);

Ghanashyam Acharya, West Lafayette, IN (US);

David Brownholland, West Lafayette, IN (US);

Inventors:

Cagri Savran, West Lafayette, IN (US);

Philip Low, West Lafayette, IN (US);

David Thompson, West Lafayette, IN (US);

Walter Henne, West Lafayette, IN (US);

Derek Doorneweerd, West Lafayette, IN (US);

Chun-Li Chang, West Lafayette, IN (US);

Ghanashyam Acharya, West Lafayette, IN (US);

David Brownholland, West Lafayette, IN (US);

Assignee:

Purdue Research Foundation, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/543 (2006.01); C12Q 1/68 (2006.01); G01N 21/47 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54386 (2013.01); C12Q 1/6804 (2013.01); G01N 21/4788 (2013.01); G01N 33/54393 (2013.01);
Abstract

Systems and methods for rapid and ultrasensitive detection of target biomolecules in a sample are presented. The detection of biomolecules is achieved through a synergistic use of immunoseparation and diffractometry, and the formation of antibody-biomolecule-ligand sandwich complexes that form diffraction gratings. Characteristic diffraction patterns are then produced upon illumination of the diffraction gratings with light. The diffraction patterns can be used to detect very low amounts of biomolecules present in the sample.


Find Patent Forward Citations

Loading…