The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9340834 B1

PDF
Full Text
Expired
Date of Patent:
May. 17, 2016

Filed:

Jul. 22, 2013
Applicant:

Cornell Research Foundation, Inc., Ithaca, NY (US);

Inventors:

Francis Barany, New York, NY (US);

Monib Zirvi, Monmouth Junction, NJ (US);

Norman P. Gerry, Philadelphia, PA (US);

Reyna Favis, Iselin, NJ (US);

Richard Kliman, Iselin, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6886 (2013.01);
Abstract

The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The present invention further relates to an oligonucleotide array comprising of a support with the plurality of oligonucleotide probes immobilized on the support, a method of using the support to detect single-base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences, and a kit for such detection, which includes the support on which the oligonucleotides have been immobilized.


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