The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2016

Filed:

Mar. 26, 2013
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Frederick Balagadde, Pasadena, CA (US);

Carl L. Hansen, Pasadena, CA (US);

Emil Kartalov, Pasadena, CA (US);

Stephen R. Quake, Stanford, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 1/18 (2006.01); C12M 1/33 (2006.01); B01L 3/00 (2006.01); C12M 3/06 (2006.01); A01P 1/00 (2006.01);
U.S. Cl.
CPC ...
C12M 39/00 (2013.01); B01L 3/5027 (2013.01); C12M 23/16 (2013.01); C12M 23/34 (2013.01); B01L 3/502738 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/10 (2013.01); B01L 2300/163 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0655 (2013.01);
Abstract

A method to suppress biofilm formation in a growth chamber of a chemostat is described. The method includes the steps of adding a lysis agent to an isolated portion of the growth chamber, and reuniting the isolated portion with the rest of the growth chamber. The microfluidic chemostat includes a growth chamber having a plurality of compartments. Each of the compartments may be fluidly isolated from the rest of the growth chamber by one or more actuatable valves. The chemostat also included a nutrient supply-line to supply growth medium to the growth chamber, and an output port to remove fluids from the growth chamber.


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