The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2016
Filed:
Apr. 06, 2004
Howard M. Grey, La Jolla, CA (US);
Alessandro Sette, La Jolla, CA (US);
John Sidney, La Jolla, CA (US);
Scott Southwood, Santee, CA (US);
Ralph T. Kubo, Carlsbad, CA (US);
Esteban Celis, Rochester, MN (US);
Robert Chesnut, Cardiff-by-the-Sea, CA (US);
W. Martin Kast, La Cañada, CA (US);
Howard M. Grey, La Jolla, CA (US);
Alessandro Sette, La Jolla, CA (US);
John Sidney, La Jolla, CA (US);
Scott Southwood, Santee, CA (US);
Ralph T. Kubo, Carlsbad, CA (US);
Esteban Celis, Rochester, MN (US);
Robert Chesnut, Cardiff-by-the-Sea, CA (US);
W. Martin Kast, La Cañada, CA (US);
Epimmune Inc., San Diego, CA (US);
Abstract
The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. One such peptide, NMLSTVLGV (SEQ ID NO: 183) is useful to elicit an immune response against influenza. The present invention also provides a heteropolymer of an isolated immunogenic peptide less than 15 amino acids in length comprising the oligopeptide NMLSTVLGV (SEQ ID NO: 183) and at least one different peptide.