The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2016
Filed:
Oct. 03, 2013
Applicant:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Inventors:
Zhong-Yin Zhang, Carmel, IN (US);
Sheng Zhang, Carmel, IN (US);
Assignee:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/06 (2006.01); A61K 38/07 (2006.01); C07K 5/087 (2006.01); C07F 9/655 (2006.01); C07F 9/6558 (2006.01); C07F 9/38 (2006.01); C07K 5/065 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/0812 (2013.01); C07F 9/3882 (2013.01); C07F 9/65522 (2013.01); C07F 9/65586 (2013.01); C07K 5/06078 (2013.01); A61K 38/00 (2013.01);
Abstract
Novel protein tyrosine phosphatase (PTP) inhibitor compounds synthesized from phosphonodifluoromethyl phenylalanine (F2Pmp) are provided. Use of these compounds for inhibiting a PTP enzyme (such as PTP-MEG2), as well as treating a disease, disorder, or condition associated with inappropriate activity of a PTP (such as type 2 diabetes), is also provided.