The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2016

Filed:

May. 05, 2014
Applicants:

University of Massachusetts, Boston, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Jon Goguen, Holden, MA (US);

Ning Pan, Boylston, MA (US);

Kyungae Lee, Newton, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 233/26 (2006.01); C07D 213/79 (2006.01); A61K 31/4164 (2006.01); A61K 31/4178 (2006.01); A61K 31/426 (2006.01); C07D 213/70 (2006.01); C07D 213/74 (2006.01); C07D 233/64 (2006.01); C07D 277/82 (2006.01); C07D 401/04 (2006.01); C07D 405/12 (2006.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
C07D 213/79 (2013.01); A61K 31/4164 (2013.01); A61K 31/4178 (2013.01); A61K 31/426 (2013.01); C07D 213/70 (2013.01); C07D 213/74 (2013.01); C07D 233/26 (2013.01); C07D 233/64 (2013.01); C07D 277/82 (2013.01); C07D 401/04 (2013.01); C07D 405/12 (2013.01); C07D 413/04 (2013.01); C12Q 1/18 (2013.01);
Abstract

The invention, in some aspects, relates to compounds and compositions useful for inhibiting Type III secretion systems in pathogenic bacteria, such as. In some aspects, the invention relates to methods for discovering inhibitors of the Type III secretion system and uses of such inhibitors in the treatment and prevention of disease.


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