The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9340488 B1

PDF
Full Text
Expired
Date of Patent:
May. 17, 2016

Filed:

Nov. 13, 2014
Applicants:

Hadasit Medical Research Services & Development Limited, Jerusalem, IL;

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Jerusalem, IL;

Inventors:

Arie Dagan, Jerusalem, IL;

Shimon Slavin, Tel Aviv, IL;

Shimon Gatt, Jerusalem, IL;

Jeremy Zahavy, Modiin, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/133 (2006.01); C07C 215/12 (2006.01); C07C 215/10 (2006.01); A61K 31/4745 (2006.01); A61K 31/513 (2006.01);
U.S. Cl.
CPC ...
C07C 215/12 (2013.01); A61K 31/133 (2013.01); A61K 31/4745 (2013.01); A61K 31/513 (2013.01); C07C 215/10 (2013.01);
Abstract

The present invention provides new ceramide analogs indicated as the compounds of formula (II). These novel analogs exhibit a significant anti cancerous effect and are therefore provided as a pharmaceutical composition for treating cell proliferative diseases, neurodegenerative disorders, metabolism-associated conditions, infectious diseases, and immune-related disorders. The invention further provides combined compositions and kits combining the novel ceramide analogs of formula (II) with an additional therapeutic agent.


Find Patent Forward Citations

Loading…