The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2016

Filed:

May. 07, 2012
Applicants:

James M. Mullin, Havertown, PA (US);

Jonathan Raines, Gladwyne, PA (US);

Inventors:

James M. Mullin, Havertown, PA (US);

Jonathan Raines, Gladwyne, PA (US);

Assignees:

Lankenau Institute for Medical Research, Wynnewood, PA (US);

Monk Street Partners LLC, Collegeville, PA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 33/30 (2006.01); A61K 31/315 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 33/30 (2013.01); A61K 31/315 (2013.01);
Abstract

Methods of inhibiting Barrett's esophagus and/or adenocarcinoma in a subject are provided. In a particular embodiment, the method comprises administering at least one composition comprising at least one zinc compound and at least one pharmaceutically acceptable carrier to the esophagus of the subject. The zinc may be a pharmaceutically acceptable salt of zinc, such as zinc gluconate. The zinc may be administered, for example, orally, topically, or by an implantable medical device. In a particular embodiment, the methods further comprise administering at least one analgesic, anesthetic, or other therapeutic agent or therapy for the treatment of Barrett's esophagus. The method may further comprise monitoring the progression of Barrett's esophagus in the subject.


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