The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2016
Filed:
Nov. 09, 2011
Applicants:
Jared Gollob, Cambridge, MA (US);
Akshay Vaishnaw, Cambridge, MA (US);
Christina Gamba-vitalo, Cambridge, MA (US);
Dinah Wen-yee Sah, Hopkinton, MA (US);
Inventors:
Jared Gollob, Cambridge, MA (US);
Akshay Vaishnaw, Cambridge, MA (US);
Christina Gamba-Vitalo, Cambridge, MA (US);
Dinah Wen-Yee Sah, Hopkinton, MA (US);
Assignee:
ALNYLAM PHARMACEUTICALS, INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/713 (2006.01); A61K 9/00 (2006.01); A61K 9/10 (2006.01); A61K 9/127 (2006.01); A61K 31/7088 (2006.01); A61K 45/06 (2006.01); A61K 31/56 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 9/0019 (2013.01); A61K 9/10 (2013.01); A61K 9/1271 (2013.01); A61K 31/56 (2013.01); A61K 31/7088 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01); C12N 15/1136 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01); C12N 2320/32 (2013.01);
Abstract
This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a liquid particle formulation, methods of using the compositions to inhibit the expression of the Eg5/KSP and VEGF, and methods of using the compositions to treat pathological processes mediated by Eg5/KSP and VEGF expression, such as endometrial cancer.