The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2016

Filed:

Jul. 08, 2014
Applicant:

Merial, Inc., Duluth, GA (US);

Inventors:

Loic Patrick Le Hir de Fallois, Atlanta, GA (US);

Hyoung Ik Lee, Cary, NC (US);

Philip Reid Timmons, Durham, NC (US);

William Glenn Cawthorne, Jr., Henderson, NC (US);

Adalberto Perez de Leon, Wake Forest, NC (US);

Assignee:

MERIAL, INC., Duluth, GA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/56 (2006.01); C07D 401/04 (2006.01); C07D 231/18 (2006.01); A01N 47/02 (2006.01); A61K 31/415 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01); A01N 25/02 (2006.01);
U.S. Cl.
CPC ...
A01N 43/56 (2013.01); A01N 25/02 (2013.01); A01N 47/02 (2013.01); A61K 31/415 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); C07D 231/18 (2013.01); C07D 401/04 (2013.01);
Abstract

Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: Ris hydrogen, cyano, halogen, R, formyl, —C(O)R, —C(O)OR, —C(O)NRR, or —C(S)NH; Ris Ror —S(O)R; Ris methyl, ethyl or C-Chaloalkyl; R, Rand Rare independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; Ris halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R, —S(O)Ror SF; Z is a nitrogen atom or C—R; Ris alkyl, haloalkyl, cycloalkyl or halocycloalkyl; Ris hydrogen, alkyl, haloalkyl or alkoxy; Ris hydrogen, alkyl, haloalkyl or alkoxy; Ris alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; Ris alkyl or haloalkyl; Ris hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.


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