The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2016

Filed:

Aug. 15, 2013
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Allen J. Ebens, Jr., San Carlos, CA (US);

Lori Friedman, San Carlos, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 39/395 (2006.01); A61K 31/33 (2006.01); A61K 31/535 (2006.01); A61K 31/70 (2006.01); G01N 33/50 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); A61K 31/519 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61K 31/33 (2013.01); A61K 31/535 (2013.01); A61K 31/70 (2013.01);
Abstract

Combinations of PI3K inhibitor compounds having Formula I and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hematopoietic malignancies. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed


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