The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Oct. 12, 2012
Applicant:
Auburn University, Auburn, AL (US);
Inventors:
Jiaming Hu, Auburn, AL (US);
Tanyu Wang, Lawrence, KS (US);
Christopher J. Easley, Auburn, AL (US);
Curtis G. Shannon, Auburn, AL (US);
Assignee:
AUBURN UNIVERSITY, Auburn, AL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 27/3275 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6825 (2013.01); G01N 27/327 (2013.01); G01N 27/3276 (2013.01);
Abstract
The present disclosure includes an electrochemical proximity assay (ECPA) which leverages two aptamer or antibody-oligonucleotide probes and proximity-dependent DNA hybridization to move a redox active molecule near an electrically conductive base. The ECPA of the present disclosure produces rapid, quantitative results, enabling point-of-care use in the detection of biomarkers of disease.