The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
May. 16, 2012
Applicants:
Pablo Gluschankof, Marseille, FR;
Christele Perrin-east, Marseille, FR;
Inventors:
Pablo Gluschankof, Marseille, FR;
Christele Perrin-East, Marseille, FR;
Assignee:
AMIKANA, BIOLOGICS, Marseille, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/06 (2006.01); C07H 19/10 (2006.01); C12Q 1/48 (2006.01); C07K 14/705 (2006.01); C12N 9/12 (2006.01); C12N 9/88 (2006.01); C12N 15/81 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/485 (2013.01); C07K 14/705 (2013.01); C12N 9/1205 (2013.01); C12N 9/1276 (2013.01); C12N 9/88 (2013.01); C12N 15/81 (2013.01); C12Y 207/01074 (2013.01); C12Y 207/07049 (2013.01); C12Y 402/01019 (2013.01);
Abstract
A transformed yeast cell includes: a nucleic acid sequence coding for a reverse transcriptase; a reverse transcription indicator; a nucleic acid sequence coding for deoxycytidine kinase (dCK); and at least one nucleic acid sequence coding for nucleoside transporter. Methods for screening a compound with the ability to inhibit reverse transcription and for predicting the sensitivity of a reverse transcriptase to a NRTI compound, particularly a reverse transcriptase derived from a virus infecting a subject using the transformed Yeast cell are also described.