The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Nov. 23, 2010
Anastasia Khvorova, Northborough, MA (US);
Annaleen Vermeulen, Lafayette, CO (US);
Rob Kaiser, Broomfield, CO (US);
Jon Karpilow, Boulder, CO (US);
Nicolaas M. J. Vermeulen, Woodinville, WA (US);
Walt Mahoney, Woodinville, WA (US);
Anastasia Khvorova, Northborough, MA (US);
Annaleen Vermeulen, Lafayette, CO (US);
Rob Kaiser, Broomfield, CO (US);
Jon Karpilow, Boulder, CO (US);
Nicolaas M. J. Vermeulen, Woodinville, WA (US);
Walt Mahoney, Woodinville, WA (US);
ELITECHGROUP B.V., Spankeren, NL;
Abstract
Compositions and methods for inhibiting the actions of non-coding RNAs such as miRNAs and piRNAs are provided. The compositions comprise single or double stranded oligonucleotides conjugated with Minor Groove Binders ('MGBs'). The oligonucleotides can vary in length, can contain nucleotides having one or more modifications, and have regions that are substantially complementary to one or more mature miRNAs or piRNAs.